Ohgi Shie, Ehara Shigeru, Satoh Takashi, Kato Sadafumi, Shimosegawa Kenji, Ishida Yoji
Department of Radiology, Iwate Medical University School of Medicine, 19-1 Uchimaru, Morioka 020-8505 Japan.
Skeletal Radiol. 2002 Feb;31(2):99-102. doi: 10.1007/s00256-001-0446-z. Epub 2001 Dec 4.
Spontaneous regression of diffuse B-cell type lymphoma of the lumbar vertebra is reported. A 61-year-old woman experienced spontaneous disappearance of a large psoas mass associated with an infiltrating process of the lumbar vertebrae. The biopsy of the residual change after spontaneous regression revealed reactive foamy histiocytes and small lymphocytes with no atypia. The lesion recurred 7 months later with no systemic treatment in the interim, when the diagnosis of lymphoma was finally made. Spontaneous regression may be related to potentiation of the host immune response, which affects tumor growth.
据报道，腰椎弥漫性B细胞型淋巴瘤出现自发消退。一名61岁女性的腰大肌巨大肿块伴随腰椎浸润性病变自发消失。自发消退后残留病变的活检显示为反应性泡沫状组织细胞和无异型性的小淋巴细胞。7个月后，在未进行全身治疗的情况下病变复发，最终确诊为淋巴瘤。自发消退可能与宿主免疫反应增强有关，而宿主免疫反应会影响肿瘤生长。
