• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Does the surface tension make the lung inherently unstable?

作者信息

Fung Y C

出版信息

Circ Res. 1975 Oct;37(4):497-502. doi: 10.1161/01.res.37.4.497.

DOI:10.1161/01.res.37.4.497
PMID:1182941
Abstract

Many authors regard the human lung as a collection of 300 million bubbles independently connected by cylindrical tubes. Under surface tension such a model is inherently unstable in the sense that the small alveoli would empty into the large ones so that the lung would consist only of collapses and hyperinflated alveoli. It has been demonstrated that this basic model is wrong. My observation is based on the well-known fact that both sides of each interalveolar septum are exposed to ventilated air. When the topological relationship between the alveolar septa is properly taken into account, it can be shown that each interalveolar septum is a minimal surface and that there is no problem of inherent instability in the sense mentioned earlier. However, the lung structure is flimsy and can become unstable in the same sense that an airplane structure or an Atlas rocket can become unstable. The clarification of lung inflation and atelectasis can proceed in a rational manner when the confusion of an erroneous model is removed.

摘要

相似文献

1
Does the surface tension make the lung inherently unstable?
Circ Res. 1975 Oct;37(4):497-502. doi: 10.1161/01.res.37.4.497.
2
Stress, deformation, and atelectasis of the lung.肺的应力、变形和肺不张
Circ Res. 1975 Oct;37(4):481-96. doi: 10.1161/01.res.37.4.481.
3
The significance of alveolar geometry and surface tension in the respiratory mechanics of the lung.肺泡几何形状和表面张力在肺呼吸力学中的意义。
Respir Physiol. 1975 Jul;24(2):115-37. doi: 10.1016/0034-5687(75)90107-3.
4
[Surface phenomena and mechanics of lung respiration].[肺呼吸的表面现象与力学]
Fortschr Med. 1973 Jun 7;91(16):698-701.
5
A mathematical model of lung parenchyma.肺实质的数学模型。
J Biomech Eng. 1980 May;102(2):124-36. doi: 10.1115/1.3138208.
6
The influence of surface active substances on alveolar mechanics in the respiratory distress syndrome.表面活性物质对呼吸窘迫综合征中肺泡力学的影响。
Respiration. 1968;25(6):441-57. doi: 10.1159/000192579.
7
["Surfactant": the surface film of pulmonary alveoli].["表面活性剂":肺泡的表面膜]
Schweiz Med Wochenschr. 1968 Aug 31;98(35):1338-42.
8
The problem of airways collapse during expiration.
Czech Med. 1980;3(2):169-75.
9
Intraalveolar bubbles and bubble films: II. Formation in vivo through adulthood.肺泡内气泡与气泡膜:II. 成年期及成年期以后在体内的形成
Anat Rec. 1996 Oct;246(2):245-70. doi: 10.1002/(SICI)1097-0185(199610)246:2<245::AID-AR12>3.0.CO;2-O.
10
Analysis of atelectasis, ventilated, and hyperinflated lung during mechanical ventilation by dynamic CT.通过动态CT分析机械通气期间的肺不张、通气肺和过度充气肺。
Chest. 2005 Nov;128(5):3757-70. doi: 10.1378/chest.128.5.3757.

引用本文的文献

1
Respiratory distress when a lung surfactant loses one of its two hydrophobic tails.当肺表面活性物质失去其两条疏水尾巴之一时出现呼吸窘迫。
Proc Natl Acad Sci U S A. 2024 Mar 5;121(10):e2320426121. doi: 10.1073/pnas.2320426121. Epub 2024 Feb 26.
2
Acinar micromechanics in health and lung injury: what we have learned from quantitative morphology.健康与肺损伤中的腺泡微力学:我们从定量形态学中学到的知识。
Front Physiol. 2023 Mar 21;14:1142221. doi: 10.3389/fphys.2023.1142221. eCollection 2023.
3
Prenatal quantification of human foetal lung and liver elasticities between 24 and 39 weeks of gestation using 2D shear wave elastography.
使用二维剪切波弹性成像技术在 24 至 39 孕周期间对胎儿肺部和肝脏的弹性进行产前定量评估。
Eur Radiol. 2022 Aug;32(8):5559-5567. doi: 10.1007/s00330-022-08654-1. Epub 2022 Mar 10.
4
A numerical study of the aerosol behavior in intra-acinar region of a human lung.人体肺部腺泡区域内气溶胶行为的数值研究。
Phys Fluids (1994). 2020 Oct 1;32(10):103305. doi: 10.1063/5.0024200.
5
Bioengineering the Blood-gas Barrier.生物工程学血液-气体屏障。
Compr Physiol. 2020 Mar 12;10(2):415-452. doi: 10.1002/cphy.c190026.
6
The micromechanics of lung alveoli: structure and function of surfactant and tissue components.肺泡的微观力学:表面活性剂和组织成分的结构与功能
Histochem Cell Biol. 2018 Dec;150(6):661-676. doi: 10.1007/s00418-018-1747-9. Epub 2018 Nov 2.
7
Mechanics of the lung in the 20th century.20 世纪的肺部力学。
Compr Physiol. 2011 Oct;1(4):2009-27. doi: 10.1002/cphy.c100067.
8
Lung parenchymal mechanics.肺实质力学。
Compr Physiol. 2011 Jul;1(3):1317-51. doi: 10.1002/cphy.c100033.
9
Direct determination of surface tension in the lung.肺表面张力的直接测定
Proc Natl Acad Sci U S A. 1976 Dec;73(12):4698-702. doi: 10.1073/pnas.73.12.4698.
10
Forced perturbation of respiratory system. B. A continuum mechanics analysis.呼吸系统的强制扰动。B. 连续介质力学分析。
Ann Biomed Eng. 1978 Dec;6(4):367-98. doi: 10.1007/BF02584546.