Karakaplan A D, Bieniek M P, Skalak R
J Biomech Eng. 1980 May;102(2):124-36. doi: 10.1115/1.3138208.
The geometry of the proposed model of the parenchyma of a mammalian lung reproduces a cluster of alveoli arranged around a lowest-level air duct. The alveolar walls are assumed to be nonlinear elastic membranes, whose properties are described in terms of a strain energy function which reflects the hardening character of the stress-strain curve. The effect of the surfactant is included in terms of a variable (area-dependent) surface tension. Analyses of various mechanical processes in the parenchyma are performed with the aid of the finite element method, with the geometric and physical nonlinearities of the problem taken into account.
所提出的哺乳动物肺实质模型的几何结构再现了围绕最低级气道排列的肺泡簇。肺泡壁被假定为非线性弹性膜,其特性通过反映应力-应变曲线硬化特性的应变能函数来描述。表面活性剂的作用通过一个可变的(与面积有关的)表面张力来体现。借助有限元方法对实质中的各种力学过程进行分析,同时考虑了问题的几何和物理非线性。