Ransohoff J, Dimattio J, Hochwald G, Epstein F
Childs Brain. 1975;1(2-3):183-6. doi: 10.1159/000119593.
Cerebral blood flow was measured by the indicator fractionation technique in normal, acute hydrocephalic, chronic compensated hydrocephalic and craniectomized hydrocephalic cats. In the five normal cats the mean total brain blood flow was 136.1 ml/min/100 g dry weight. The six acute hydrocephalic animals demonstrated a relatively uniform 22% reduction in total blood flow. In eight chronic hydrocephalic cats CBF increased to the point where there was only an overall 7% decrease. In three hydrocephalic and craniectomized cats the CBF was reduced by 30.6%. In the acute phases there was a decrease in the number of blood vessels. Chronic compensated hydrocephalic brains had somewhat more vessels than the normal, whereas the craniectomized, massively hydrocephalic brain had a dramatic increase in both the number and caliber of blood vessels. These results clearly demonstrate that in acute obstructive hydrocephalus in cats, there is a significant decrease in CBF. The blood vessels revert to normal in shunted cats.
采用指示剂分离技术对正常猫、急性脑积水猫、慢性代偿性脑积水猫和去骨瓣脑积水猫的脑血流量进行了测量。在5只正常猫中，平均全脑血流量为136.1毫升/分钟/100克干重。6只急性脑积水动物的全脑血流量相对均匀地减少了22%。在8只慢性脑积水猫中，脑血流量增加到仅总体减少7%的程度。在3只去骨瓣脑积水猫中，脑血流量减少了30.6%。急性期血管数量减少。慢性代偿性脑积水的大脑血管比正常大脑略多，而去骨瓣的大量脑积水大脑的血管数量和管径都显著增加。这些结果清楚地表明，在猫的急性梗阻性脑积水中，脑血流量显著降低。分流后的猫血管恢复正常。
