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[儿茶酚胺作用下平滑肌细胞对Ca45和Na22同位素膜通透性变化的研究]

[Study of the changes in the membrane permeability of smooth muscle cells for Ca45 and Na22 isotopes under the action of catecholamines].

作者信息

Abramets I I, Shovtuta V I

出版信息

Farmakol Toksikol. 1975 Sep-Oct;38(5):543-7.

PMID:1183583
Abstract

Relaxation of smooth muscles of the stomachal band, but not of the portal vein of rats, induced with isadrine, is accompanied by a reduced entrance of Ca45 into the cells, this process, however, being barred by propranol. Contraction of smooth muscles of the seminal duct, aortic band and that of the portal vein of the rats, induced by norepinephrine is attended by an intensified incorporation of Ca45 in the cells, which diminishes in the presence of phentolamine. Norepinephrine stimulates an insignificant increase of the Na22 entrance into the cells of the portal vein and does not produce any regular changes in the movement of this isotope in the cells of the seminal duct of the rats.

摘要

用异丙肾上腺素诱导大鼠胃带平滑肌松弛,但门静脉平滑肌不松弛,同时伴有Ca45进入细胞的减少,然而,这一过程被普萘洛尔阻断。去甲肾上腺素诱导大鼠输精管、主动脉带和门静脉平滑肌收缩,同时伴有Ca45在细胞内的掺入增加,在酚妥拉明存在时这种增加会减少。去甲肾上腺素刺激门静脉细胞对Na22的摄取略有增加,并且对大鼠输精管细胞中该同位素的移动没有产生任何规律性变化。

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