Temnialov N D, Abramets I I
Farmakol Toksikol. 1978 May-Jun;41(3):296-8.
Tests conducted on aortic strips of rabbits, portal veins and musculus rectococcygeus in rats showed the urea to nonspecifically increase the effects of norepinephrine at the expense of a greater calcium permeability of membranes and, possibly, also at the expense of a higher sensitivity of the myosin adenosine-triphosphatase to the action of calcium ions without affecting the function of adrenoreceptors.
在兔主动脉条、大鼠门静脉和直肠尾骨肌上进行的试验表明,尿素可非特异性地增强去甲肾上腺素的作用,代价是膜的钙通透性增加,并且可能还以肌球蛋白三磷酸腺苷酶对钙离子作用的更高敏感性为代价,而不影响肾上腺素能受体的功能。