微穗羊蹄甲（拉迪）麦克布（豆科）的植物化学与药理学分析
Phytochemical and pharmacological analysis of Bauhinia microstachya (Raddi) Macbr. (Leguminosae).
作者信息
Meyre-Silva C, Yunes R A, Delle Monache F, Santos A R, Schmeling L O, Gadotti V M, Liz F, Cechinel-Filho V
机构信息
Departamento de Química, Universidade Federal de Santa Catarina UFSC, Florianópolis, SC, Brazil.
出版信息
Z Naturforsch C J Biosci. 2001 Nov-Dec;56(11-12):939-42.
This paper describes the isolation of four phytoconstituents from the leaves of Bauhinia microstachya, a Brazilian medicinal plant used in folk medicine for the treatment of several ailments. Based on spectroscopic evidence, these compounds were identified as methyl gallate (1), kaempferol 3-O-rhamnosyl (2), quercitrin (3) and myricitrin (4). The crude methanolic extract and two compounds (3 and 4) were tested as analgesic using the writhing test in mice. The extract and compound 3 caused potent and dose-related analgesic effects, confirming the popular use of this plant for the treatment dolorous processes.
本文描述了从巴西药用植物小花羊蹄甲的叶子中分离出四种植物成分，这种植物在民间医学中用于治疗多种疾病。基于光谱证据，这些化合物被鉴定为没食子酸甲酯（1）、山柰酚3 - O - 鼠李糖苷（2）、槲皮苷（3）和杨梅苷（4）。使用小鼠扭体试验，对粗甲醇提取物和两种化合物（3和4）进行了镇痛测试。提取物和化合物3产生了强效且与剂量相关的镇痛作用，证实了这种植物在治疗疼痛过程中的广泛应用。
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