一个约400 kb的细菌人工染色体（BAC）重叠群包含牛的经典I类主要组织相容性复合体（MHC）基因。
A BAC contig of approximately 400 kb contains the classical class I major histocompatibility complex (MHC) genes of cattle.
作者信息
Di Palma F, Archibald S D, Young J R, Ellis S A
机构信息
NIDCD, National Institutes of Health, Rockville, MD 20850-3227, USA.
出版信息
Eur J Immunogenet. 2002 Feb;29(1):65-8. doi: 10.1046/j.1365-2370.2002.00272.x.
Abstract
A cattle BAC library derived from an MHC homozygous animal was screened for MHC class I genes. This revealed at least nine class I-related genes in a contig spanning approximately 400 kb, and several additional genes on other clones. The three classical class I genes expressed on this haplotype (A14) were shown to be distributed over a region at most 212 kb apart.
摘要
对源自 MHC 纯合动物的牛 BAC 文库进行了 MHC I 类基因筛选。这揭示了在一个跨度约 400 kb 的重叠群中至少有九个 I 类相关基因，以及其他克隆上的几个额外基因。在该单倍型（A14）上表达的三个经典 I 类基因被证明分布在相距最多 212 kb 的区域内。
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