Erlangen C B
Infusionsther Klin Ernahr Sonderh. 1975;3:4-6.
The author reports the successful treatment with Vivasorb, the bulk-free, balanced synthetic diet, of patients with severe forms of ulcerative colitis and Crohn's disease, indigenous sprue and condition after small bowel resection, and of one patient with a Cronkhite Canada syndrome. The duration of the treatment was from a few weeks to 34 months. The patients received between 320 and 640 g/day, according to their requirements and their tolerance. Because of the relatively low content of essential fatty acids, long-term exclusive administration of Vivasorb may lead to symptoms of essential fatty acid deficiency, which disappear after the administration of Lipofundin S. The successful treatment of patients with malabsorption syndrome was verified histologically. Particles of mucosa taken from different small bowel sections showed the development of villi after only four weeks of treatment, whereas, before the treatment, subtotal villi atrophy had been observed.
作者报告了使用无渣、均衡的合成饮食Vivasorb成功治疗重度溃疡性结肠炎、克罗恩病、原发性口炎性腹泻以及小肠切除术后状况的患者，以及1例加拿大克朗凯特综合征患者。治疗持续时间从数周至34个月不等。患者根据自身需求和耐受情况，每天摄入320至640克。由于必需脂肪酸含量相对较低，长期单独使用Vivasorb可能会导致必需脂肪酸缺乏症状，补充Lipofundin S后这些症状会消失。吸收不良综合征患者的成功治疗通过组织学得到证实。取自不同小肠段的黏膜颗粒显示，仅治疗四周后绒毛就有所发育，而治疗前观察到的是绒毛大部萎缩。
