Smith Caroline, Crowther Caroline, Beilby Justin
Department of Obstetrics & Gynaecology, Adelaide University, Adelaide, Australia.
Birth. 2002 Mar;29(1):1-9. doi: 10.1046/j.1523-536x.2002.00149.x.
Nausea and vomiting in early pregnancy are troublesome symptoms for some women. We undertook a single blind randomized controlled trial to determine whether acupuncture reduced nausea, dry retching, and vomiting, and improved the health status of women in pregnancy.
The trial was undertaken at a maternity teaching hospital in Adelaide, Australia, where 593 women less than 14 weeks' pregnant with symptoms of nausea or vomiting were randomized into 4 groups: traditional acupuncture, pericardium 6 (p6) acupuncture, sham acupuncture, or no acupuncture (control). Treatment was administered weekly for 4 weeks. The primary outcomes were nausea, dry retching, vomiting, and health status. Comparisons were made between groups over 4 consecutive weeks.
Women receiving traditional acupuncture reported less nausea (p < 0.01) throughout the trial and less dry retching (p < 0.01) from the second week compared with women in the no acupuncture control group. Women who received p6 acupuncture (p < 0.05) reported less nausea from the second week of the trial, and less dry retching (p < 0.001) from the third week compared with women in the no acupuncture control group. Women in the sham acupuncture group (p < 0.01) reported less nausea and dry retching (p < 0.001) from the third week compared with women in the no acupuncture group. No differences in vomiting were found among the groups at any time.
Acupuncture is an effective treatment for women who experience nausea and dry retching in early pregnancy. A time-related placebo effect was found for some women.
妊娠早期的恶心和呕吐对一些女性来说是令人困扰的症状。我们进行了一项单盲随机对照试验,以确定针灸是否能减轻恶心、干呕和呕吐,并改善孕期女性的健康状况。
该试验在澳大利亚阿德莱德的一家妇产教学医院进行,将593名怀孕少于14周且有恶心或呕吐症状的女性随机分为4组:传统针灸组、心包经6穴位(p6)针灸组、假针灸组或不进行针灸组(对照组)。每周进行一次治疗,持续4周。主要结局指标为恶心、干呕、呕吐和健康状况。连续4周对各组进行比较。
与不进行针灸的对照组女性相比,接受传统针灸的女性在整个试验期间报告的恶心症状较少(p<0.01),从第二周起干呕症状较少(p<0.01)。与不进行针灸的对照组女性相比,接受p6针灸的女性从试验第二周起报告的恶心症状较少(p<0.05),从第三周起干呕症状较少(p<0.001)。与不进行针灸组的女性相比,假针灸组的女性从第三周起报告的恶心和干呕症状较少(p<0.01和p<0.001)。各组在任何时候的呕吐情况均无差异。
针灸是治疗妊娠早期恶心和干呕女性的有效方法。发现对一些女性存在与时间相关的安慰剂效应。