脑膜炎球菌血症和脑膜炎球菌性脑膜炎不良因素的比较研究。
A comparative study of adverse factors in meningococcaemia and meningococcal meningitis.
作者信息
Ansari B M, Davies D B, Boyce J M
出版信息
Postgrad Med J. 1979 Nov;55(649):780-3. doi: 10.1136/pgmj.55.649.780.
In a retrospective study, a comparison was made of clinical and laboratory data in 14 patients with meningococcaemia and 40 patients with meningococcal meningitis. Significant differences were found in duration of symptoms, onset of purpura, presence of shock, initial WBC, ESR, and serum fibrin degradation products. The overall mortality rate in this series was 7%, 4 patients with meningococcaemia dying, but none with meningococcal meningitis. This study indicates the importance of clinical and pathological grading of patients with meningococcaemia. Death occurred only in patients presenting with 3 or more of the adverse factors detailed.
在一项回顾性研究中，对14例脑膜炎球菌血症患者和40例脑膜炎球菌性脑膜炎患者的临床和实验室数据进行了比较。在症状持续时间、紫癜出现时间、休克情况、初始白细胞计数、红细胞沉降率和血清纤维蛋白降解产物方面发现了显著差异。该系列研究中的总死亡率为7%，4例脑膜炎球菌血症患者死亡，但脑膜炎球菌性脑膜炎患者无一死亡。这项研究表明了对脑膜炎球菌血症患者进行临床和病理分级的重要性。仅在出现3种或更多所述不利因素的患者中发生死亡。
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