Ishihara H, Kanamori M, Kawaguchi Y, Osada R, Ohmori K, Matsui H
Department of Orthopaedic Surgery, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930-0194, Japan.
J Orthop Sci. 2001;6(5):385-9. doi: 10.1007/s007760170003.
The effectiveness of hyperbaric oxygen therapy (HBO) in predicting neurological recovery in patients with spinal cord injury was evaluated. HBO has been used to treat spinal cord injury, but HBO does not appear to greatly alter the neurological outcome. This is the first report of the use of HBO as a diagnostic tool to evaluate neurological recovery after spinal cord injury. The study group consisted of 22 patients, aged 21-73 years, with spinal cord injuries. The effect of HBO was evaluated on admission and categorized as one of four grades (excellent, good, fair, or poor). The neurological status was evaluated on admission and at the time of follow-up, according to Frankel grade and the American Spinal Injury Association (ASIA) motor score. Correlations between the HBO effect and Frankel grade recovery and correlations between the HBO effect and recovery rate of the ASIA motor score were evaluated. The recovery in Frankel grade from admission to the final follow-up became better as the effectiveness of HBO increased (r = 0.445; P = 0.0414). The Frankel grade (r = 0.036; P = 0.871) and ASIA motor score (r = 0.029; P = 0.893) on admission did not correlate with the recovery in Frankel grade. There was a significant correlation between the HBO effect and the recovery rate of the ASIA motor score (r = 0.586; P = 0.0072), but this correlation was weaker than that for the ASIA motor score on admission (r = 0.752; P = 0.0006). We conclude that HBO can be employed to assess the status of spinal cord function recovery after spinal cord injury.
评估了高压氧疗法（HBO）在预测脊髓损伤患者神经功能恢复方面的有效性。HBO已被用于治疗脊髓损伤，但HBO似乎并未显著改变神经功能结局。这是关于将HBO用作评估脊髓损伤后神经功能恢复的诊断工具的首份报告。研究组由22例年龄在21至73岁之间的脊髓损伤患者组成。在入院时评估HBO的效果，并将其分为四个等级之一（优、良、中、差）。根据Frankel分级和美国脊髓损伤协会（ASIA）运动评分，在入院时和随访时评估神经状态。评估HBO效果与Frankel分级恢复之间的相关性以及HBO效果与ASIA运动评分恢复率之间的相关性。从入院到最终随访，随着HBO有效性的增加，Frankel分级的恢复情况变得更好（r = 0.445；P = 0.0414）。入院时的Frankel分级（r = 0.036；P = 0.871）和ASIA运动评分（r = 0.029；P = 0.893）与Frankel分级的恢复无关。HBO效果与ASIA运动评分恢复率之间存在显著相关性（r = 0.586；P = 0.0072），但这种相关性弱于入院时的ASIA运动评分（r = 0.752；P = 0.0006）。我们得出结论，HBO可用于评估脊髓损伤后脊髓功能恢复的状况。
