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年龄与噪声性听力损失

Age and noise-induced hearing loss.

作者信息

Toppila E, Pyykkö I, Starck J

机构信息

Department of Physics, Finnish Institute of Occupational Health, Helsinki.

出版信息

Scand Audiol. 2001;30(4):236-44. doi: 10.1080/01050390152704751.

Abstract

The purpose of the study was to evaluate the effect of noise, age and confounders in noise-induced hearing loss (NIHL). Information about work exposure, the use of hearing protective devices, audiogram, environmental and biological factors was collected from 406 paper mill workers exposed to noise levels of 91-94 dB(A), 124 forest workers exposed to noise levels of 96-99 dB(A) and 176 shipyard workers exposed to noise levels 95-97 dB(A). In addition to noise exposure, we collected the following confounders: smoking habits, serum cholesterol, systolic or diastolic blood pressure and use of analgesics. Subjects were classified based on median values, into high- and low-risk groups. The confounders were a significant source of hearing loss (HL) in younger and elderly groups of subjects, serum cholesterol level being the most important. In risk analysis the confounders partly masked the effects of noise in the development of HL. For subjects with less than two confounders, occupational noise exposure determined the development of NIHL. As the number of confounders increased, the noise exposure was overruled by these factors in the development of HL. In analysis where the subjects were matched with pairs by age, exposure, blood pressure and serum cholesterol level, the elderly subjects were more susceptible to NIHL than younger subjects. Factors independently but causally related to age were important in the development of NIHL among workers exposed to noise levels below 98 dB(A).

摘要

该研究的目的是评估噪声、年龄及混杂因素在噪声性听力损失(NIHL)中的作用。收集了406名暴露于91 - 94 dB(A)噪声水平的造纸厂工人、124名暴露于96 - 99 dB(A)噪声水平的林业工人以及176名暴露于95 - 97 dB(A)噪声水平的造船厂工人的工作暴露信息、听力保护装置使用情况、听力图、环境和生物学因素。除噪声暴露外,还收集了以下混杂因素:吸烟习惯、血清胆固醇、收缩压或舒张压以及镇痛药使用情况。根据中位数将研究对象分为高风险组和低风险组。混杂因素是年轻和老年研究对象听力损失(HL)的重要来源,血清胆固醇水平最为重要。在风险分析中,混杂因素在一定程度上掩盖了噪声在HL发生发展中的作用。对于混杂因素少于两个的研究对象,职业噪声暴露决定了NIHL的发生。随着混杂因素数量的增加,在HL的发生发展中这些因素超过了噪声暴露的影响。在按年龄、暴露、血压和血清胆固醇水平进行配对分析时,老年研究对象比年轻研究对象更容易患NIHL。在暴露于低于98 dB(A)噪声水平的工人中,与年龄独立且有因果关系的因素在NIHL的发生发展中很重要。

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