Chen L, Wang Y, Jin Y
Xuanwu Hospital of Capital University of Medical Sciences, Beijing 100053, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2001 Dec;22(6):414-7.
To understand the situation of drug use, drug request, combination of drugs and daily drug dose (DDD) among elderly patients, to provide scientific evidences for safely, effectively, economically and rationally on disease prevention and improving the quality of life of the elderly patients.
A 2-year(1998-1999) prescriptions database which was set up according to different departments of consultation, patient age, sex, consultation date, and name of drugs, dosage was used for the study. Prescriptions were randomly selected on 3-4 days in every month, from 22 hospitals in Beijing. FOXPRO software was used for statistics and analyses. Information of elderly patients (> or = 60 year) on status of drug use, was collected and compared with general patients.
The proportion of elderly patients' prescription was 19.9%, with an average number of drugs prescribed in elderly patients 2.71, which was 0.27 higher than that of the general patients. Proportion of injections per every hundred elderly patients prescriptions was 18.4%. The major kinds of drugs were those related to cardiovasculars and vitamins. The most frequent drug was vitamin E nicotinate. DDD on elderly patients was lower than that defined by WHO and drug instruction, but higher than that of the general patients during the same period and was increasing. Daily dose of anti-hypertensions was also higher. The rate of consultation for cardiovascular diseases was high. The ratio of drugs in accordance with national essential drug list was 87.5%.
The rates of elderly patients' prescription, average number of drugs per prescription, proportion of injections and DDD were high. The rational drug use on elderly patients should be given more concerns.
了解老年患者用药情况、用药需求、药物联用及日规定剂量(DDD),为安全、有效、经济、合理地预防疾病及提高老年患者生活质量提供科学依据。
采用依据不同科室、患者年龄、性别、就诊日期及药品名称、剂量建立的2年(1998 - 1999年)处方数据库进行研究。每月随机抽取3 - 4天,从北京22家医院抽取处方。使用FOXPRO软件进行统计分析。收集老年患者(≥60岁)用药状况信息,并与普通患者进行比较。
老年患者处方比例为19.9%,老年患者平均每张处方用药品种数为2.71种,比普通患者多0.27种。每百名老年患者处方中注射剂比例为18.4%。主要用药种类为心血管类及维生素类。最常用药物为烟酸占替诺。老年患者的DDD低于WHO及药品说明书规定,但高于同期普通患者且呈上升趋势。抗高血压药日剂量也较高。心血管疾病就诊率高。符合国家基本药物目录的药品比例为87.5%。
老年患者处方率、每张处方平均用药品种数、注射剂比例及DDD较高。应更加关注老年患者合理用药问题。