Ogilvie R W, Balentine J D
J Neurosurg. 1975 Aug;43(2):156-61. doi: 10.3171/jns.1975.43.2.0156.
Adult female rats were exposed to 60 psig of 100% oxygen for 60 minutes. Oxygen tensions in the gray matter of the lumbosacral enlargement of the spinal cord, electroenecephalograms, electrocardiograms, and respirations were monitored before, during, and after the compression periods. Oxygen tensions were found to rise sharply to as high as 1050 mm Hg during compression and remained at significantly high levels throughout the entire hour of exposure. These data support the hypothesis that spinal cord lesions induced by exposure to hyperbaric oxygen are the result of excessive tissue oxygenation.
成年雌性大鼠暴露于60磅/平方英寸的纯氧环境中60分钟。在压迫期之前、期间和之后，对脊髓腰骶膨大处灰质的氧张力、脑电图、心电图和呼吸进行监测。发现在压迫期间氧张力急剧上升至高达1050毫米汞柱，并在整个暴露的一小时内保持在显著的高水平。这些数据支持了这样的假设，即暴露于高压氧引起的脊髓损伤是组织过度氧合的结果。
