Haab François, Hermieu Jean-François, Amarenco Gérard
Service d'urologie Hôpital Tenon 75970 Paris.
Rev Prat. 2002 Jan 1;52(1):28-31.
Interstitial cystitis is a disease characterized by pain occurring as the urinary bladder is gradually filling up. Its pathophysiology is unknown. The cause could be either a membrane permeability disorder, a mast cell disturbance in the bladder wall, or an autoimmune process involving the bladder. The diagnosis is essentially clinical but endoscopies and biopsies are required to rule out vesical cancers. Treatments is difficult and based on a combination of sanitary and dietary regimens, as well as drugs administered orally or infused within the bladder. Surgical treatment must remain exceptional.
间质性膀胱炎是一种在膀胱逐渐充盈时出现疼痛为特征的疾病。其病理生理学尚不清楚。病因可能是膜通透性障碍、膀胱壁肥大细胞紊乱,或涉及膀胱的自身免疫过程。诊断主要依靠临床,但需要进行内镜检查和活检以排除膀胱癌。治疗困难,基于卫生和饮食方案的组合,以及口服或膀胱内注入的药物。手术治疗必须极为罕见。