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“肉毒杆菌毒素A”治疗脑瘫儿童的短期效果:踝关节的运动学和动力学方面

Short-term effects of "botulinum toxin a" as treatment for children with cerebral palsy: kinematic and kinetic aspects at the ankle joint.

作者信息

Galli M, Crivellini M, Santambrogio G C, Fazzi E, Motta F

机构信息

Department of Bioengineering, Polytechnic of Milan, Italy.

出版信息

Funct Neurol. 2001 Oct-Dec;16(4):317-23.

Abstract

Botulinum toxin A (BTA) therapy plays several roles in the management of paediatric cerebral palsy (CP). However, few studies contain objective documentation of gait changes. The main aim of this study was to provide objective information on the outcome of the treatment. Gait analysis data from 20 normal subjects and 23 CP children were collected before and after BTA injections into the gastrocnemius-soleus complex. The follow up was performed 1 month after the first injection. The kinematic and kinetic data revealed significant improvements in dynamic ankle dorsiflexion, both in stance and in the swing phase, an improvement of equinus foot upon initial contact and better support in stance. The results of this study are promising, but studies of other joints involved in gait, such as the knee, are also needed.

摘要

A型肉毒毒素(BTA)疗法在小儿脑性瘫痪(CP)的治疗中发挥着多种作用。然而,很少有研究包含步态变化的客观记录。本研究的主要目的是提供关于该治疗效果的客观信息。在向腓肠肌-比目鱼肌复合体注射BTA之前和之后,收集了20名正常受试者和23名CP儿童的步态分析数据。在首次注射后1个月进行随访。运动学和动力学数据显示,在站立期和摆动期,动态踝关节背屈均有显著改善,初始接触时马蹄足得到改善,站立期支撑更好。本研究结果很有前景,但也需要对步态中涉及的其他关节(如膝关节)进行研究。

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