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肉毒杆菌毒素治疗腓肠肌痉挛对近端关节的定量影响:一项4岁患儿的病例研究。

Quantitative effects on proximal joints of botulinum toxin treatment for gastrocnemius spasticity: a 4-year-old case study.

作者信息

Cimolin Veronica, Galli Manuela, Crivellini Marcello, Albertini Giorgio

机构信息

Bioengineering Department, Politecnico di Milano, Piaza Leonardo da Vinci 32, 20133 Milano, Italy.

出版信息

Case Rep Med. 2009;2009:985717. doi: 10.1155/2009/985717. Epub 2009 Aug 26.

Abstract

Botulinum toxin A (BTA) is a recognized treatment for the early management of spasticity in children with Cerebral Palsy. This study quantified with Gait Analysis (GA) the gait pattern of a 4-year-old diplegic child with calf contracture before, 5 days, and 3 months after BTA injections into gastrocnemius. Kinematic and kinetic data of main lower limb joints were investigated. After only 5 days, ankle dorsi-plantarflexion and knee flex-extension improved, but hip joint worsened, increasing its excessive flexion, to compensate the improvement in knee position of the treated limb and to obtain better stability. A worsening of hip power happened. After 3 months, all joints generally improved their position during gait cycle. Hip and knee joints increased their range of movement and improvements occurred at ankle kinematics and kinetisc, too; a better ankle position and an increase of its capacity of propulsion during terminal stance were evident.

摘要

A型肉毒杆菌毒素(BTA)是公认的用于早期治疗脑瘫患儿痉挛的方法。本研究通过步态分析(GA)对一名4岁双侧痉挛型脑瘫且伴有小腿挛缩的儿童在腓肠肌注射BTA之前、注射后5天和3个月时的步态模式进行了量化。研究了主要下肢关节的运动学和动力学数据。仅5天后,踝关节背屈-跖屈和膝关节屈伸情况有所改善,但髋关节情况恶化,过度屈曲增加,以补偿治疗侧肢体膝关节位置的改善并获得更好的稳定性。髋关节力量变差。3个月后,所有关节在步态周期中的位置总体上有所改善。髋关节和膝关节的活动范围增加,踝关节的运动学和动力学也有所改善;在终末支撑期,踝关节位置更好,推进能力增强。

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Botulinum toxin in the management of the lower limb in cerebral palsy.肉毒杆菌毒素在脑瘫下肢治疗中的应用
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