[人及小鼠白内障晶状体上皮细胞凋亡的超微结构]
[The ultrastructure of human and mouse cataractous lens epithelial cell apoptosis].
作者信息
Chen F, Chen C, Song X
机构信息
Beijing Institute of Ophthalmology, Beijing 100005, China.
出版信息
Zhonghua Yan Ke Za Zhi. 2000 Mar;36(2):107-8, 10.
OBJECTIVE
To observe the relation between human senile cataract, mouse congenital cataract and lens epithelial cell apoptosis.
METHODS
Transmission electron microscope was used to observe the apoptotic morphology of the lens epithelial cells in 4 cases with senile cataract and in 2 mice with congenital cataract. The comparisons were made between the cataractous and normal transparent lens epithelial cells in human being and mice.
RESULTS
The apoptotic cells were found in senile cataract and mouse congenital cataract lens epithelial cells, while in all control lens epithelial cells they were few.
CONCLUSION
Lens epithelial cells apoptosis is related to senile cataract and mouse congenital cataract formation.
目的
观察人类老年性白内障、小鼠先天性白内障与晶状体上皮细胞凋亡之间的关系。
方法
应用透射电子显微镜观察4例老年性白内障患者及2只先天性白内障小鼠晶状体上皮细胞的凋亡形态。对人类和小鼠白内障晶状体上皮细胞与正常透明晶状体上皮细胞进行比较。
结果
在老年性白内障和小鼠先天性白内障晶状体上皮细胞中发现凋亡细胞，而在所有对照晶状体上皮细胞中凋亡细胞较少。
结论
晶状体上皮细胞凋亡与老年性白内障和小鼠先天性白内障的形成有关。
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