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[一例采用同卵双胞胎兄弟活体供肺移植治疗的多发性肺大疱病例]

[A case of multiple emphysematous bullae treated with living-donor lung transplantation from identical twin brothers].

作者信息

Miwa T, Maruyama M, Matsui S, Taniguchi H, Oda H, Arai N, Kashii T, Yamashita N, Kobayashi M, Hara H, Izumi S, Takazakura E, Tsuji H, Minami M, Miyoshi S, Matsuda H

机构信息

First Department of Internal Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University.

出版信息

Nihon Kokyuki Gakkai Zasshi. 2001 Nov;39(11):877-81.

PMID:11855089
Abstract

A 30-year-old man with multiple emphysematous bullae and bronchiectasis was admitted to Toyama Medical and Pharmaceutical University Hospital because of exertional dyspnea and fever. His chest radiograph and CT scan revealed multiple large bullae in the right lung and infiltrative shadows in the left middle lung field. Pseudomonas aeruginosa was isolated from his sputum culture. Although standard therapies including various antibiotics were administered, his respiratory condition was exacerbated, accompanied with the enlargement of bullae in the right lung and the consequent shift of the mediastinum to the left. The patient and his family proposed lung transplantation, and we concluded that lung transplantation would be an appropriate treatment for his disease. We transported the patient to Osaka University Hospital. Living-donor lung transplantation from the patient's identical twin brothers was successfully performed.

摘要

一名患有多个肺大疱和支气管扩张的30岁男性因劳力性呼吸困难和发热入住富山医科药科大学医院。他的胸部X光片和CT扫描显示右肺有多个大疱,左中肺野有浸润性阴影。痰培养分离出铜绿假单胞菌。尽管给予了包括各种抗生素在内的标准治疗,但他的呼吸状况仍恶化,同时右肺大疱增大,导致纵隔向左移位。患者及其家属提出进行肺移植,我们得出结论,肺移植将是治疗他疾病的合适方法。我们将患者转运至大阪大学医院。成功进行了来自患者同卵双胞胎兄弟的活体供肺移植。

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