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[传染性单核细胞增多症患者外周血淋巴细胞中的核酸含量]

[Nucleic acid content in peripheral blood lymphocytes from patients with infectious mononucleosis].

作者信息

Urazova O I, Novitskiĭ V V, Pomogaeva A P, Naslednikova I O, Shevtsova N M

出版信息

Klin Lab Diagn. 2002 Jan(1):43-4.

PMID:11855342
Abstract

An increase in RNA content in peripheral blood lymphocytes and increased number of macronuclear weakly basophilic cells (presumably due to increased content of B-lymphocytes which, in contrast to sharply basophilic T-lymphocytes, are characterized by light basophilic cytoplasm) are observed in patients with infectious mononucleosis. Macronuclear forms represented equally by hyper- and hypobasophilic elements predominate the structure of atypical mononuclears. Increased content of DNA in the peripheral blood lymphocytes is due to increased number of cells with high DNA content in the patient's blood and appearance of cells with 52-65 arb. units DNA (blast-transformed atypical mononuclears infected with the virus) which are normally absent.

摘要

传染性单核细胞增多症患者外周血淋巴细胞的RNA含量增加,大核弱嗜碱性细胞数量增多(可能是由于B淋巴细胞含量增加,与嗜碱性强的T淋巴细胞相比,B淋巴细胞的特征是细胞质嗜碱性淡)。非典型单核细胞的结构中,以嗜碱性过强和嗜碱性过弱成分均等代表的大核形态占主导。外周血淋巴细胞中DNA含量增加是由于患者血液中DNA含量高的细胞数量增加以及出现了正常情况下不存在的DNA含量为52 - 65任意单位的细胞(被病毒感染的母细胞转化的非典型单核细胞)。

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