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氟哌利多-芬太尼与戊巴比妥联合作用对大鼠进行深度麻醉。

Deep anesthesia in the rat with the combined action of droperidol-fentanyl and pentobarbital.

出版信息

Lab Anim Sci. 1975 Oct;25(5):585-7.

PMID:1186103
Abstract

A combination of droperidol-fentanyl and pentobarbital, administered ip, was used to obtain a state of deep anesthesia in rats for purposes of radionuclide imaging, as well as for various surgical procedures. Two or more hr of anesthesia were easily obtained. A 7.2% mortality rate (3/42) was experienced in a 3-mo study in which 5.2 procedures per rat were performed. The duration of anesthesia was found to vary both with sex and with the time of day at which the drugs were administered.

摘要

氟哌利多-芬太尼与戊巴比妥联合腹腔注射,用于使大鼠达到深度麻醉状态,以进行放射性核素成像以及各种外科手术。轻松获得了两小时或更长时间的麻醉效果。在一项为期3个月的研究中,对每只大鼠进行5.2次手术,死亡率为7.2%(42只中有3只)。研究发现,麻醉持续时间因性别以及给药时间的不同而有所差异。

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