特发性血小板减少性紫癜中的人类白细胞抗原

HLA antigens in idiopathic thrombocytopenic purpura.

作者信息

Veenhoven W A, Sijpesteijn J A, van der Schans G S

出版信息

Acta Haematol. 1979;62(3):153-8. doi: 10.1159/000207562.

DOI:10.1159/000207562

Abstract

A group of 40 patients with idiopathic thrombocytopenic purpura (ITP) was examined. Typing for HLA A and B antigens was performed. The frequencies of 24 HLA antigens in this group were compared with those of a group of 13 patients with drug-induced thrombocytopenia and two large groups of healthy controls. Differences of statistical significance between these groups were not found. Thus, associations of ITP and particular HLA antigens were not observed. The associations reported by others could not be confirmed.

摘要

对一组40例特发性血小板减少性紫癜（ITP）患者进行了检查。进行了HLA A和B抗原分型。将该组中24种HLA抗原的频率与一组13例药物性血小板减少症患者及两组健康对照者的频率进行了比较。未发现这些组之间存在统计学显著差异。因此，未观察到ITP与特定HLA抗原之间的关联。其他人报道的关联无法得到证实。