Smythe Elizabeth
School of Life Sciences, Division of Cell Biology and Immunology, Wellcome Trust Biocentre, University of Dundee, Dundee, United Kingdom.
Mol Cell. 2002 Feb;9(2):205-6. doi: 10.1016/s1097-2765(02)00462-8.
The rab family of small GTPases has numerous roles in intracellular transport including budding, tethering, and fusion of vesicles as well as organelle motility. New data show that cargo proteins are also rab effectors and can therefore regulate their own trafficking by direct interactions with the transport machinery.
小GTP酶的Rab家族在细胞内运输中具有多种作用，包括囊泡的出芽、拴系和融合以及细胞器运动。新数据表明，货物蛋白也是Rab效应器，因此可以通过与运输机制的直接相互作用来调节自身的运输。
