Evseenko D A, Tsirel'nikov N I
Laboratory of Fetoplacental Pathology, Research Center for Clinical and Experimental Medicine, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
Bull Exp Biol Med. 2001 Nov;132(5):1055-7. doi: 10.1023/a:1017908322856.
We studied erythropoiesis in newborn infants delivered by mothers with normal pregnancy and gestosis. The effects of placental extracts on hemopoiesis in JCR mice were also evaluated. Our results suggest that the placenta is involved in the regulation of fetal erythropoiesis. The placenta activates fetal erythropoiesis during physiological pregnancy, while in pregnant women with gestosis the erythropoiesis-stimulating effect of placentas was less pronounced, which probably determines low reticulocyte content in the umbilical blood.
我们研究了正常妊娠和妊娠中毒症母亲所分娩新生儿的红细胞生成情况。还评估了胎盘提取物对JCR小鼠造血的影响。我们的结果表明，胎盘参与胎儿红细胞生成的调节。在生理妊娠期间，胎盘激活胎儿红细胞生成，而在患有妊娠中毒症的孕妇中，胎盘的促红细胞生成作用不太明显，这可能决定了脐血中网织红细胞含量较低。
