Functional peculiarities of MAP2 in DBA/2J inbred mice as a component of genetic predisposition to seizures.
作者信息
Chulanova T A, Echikov S N, Sadovnikov V B, Shchipakina T G
机构信息
Group of the Mechanisms of Synaptic Transmission, Institute of Theoretical and Experimental Biophysics, Pushchino.
出版信息
Bull Exp Biol Med. 2001 Nov;132(5):1058-61. doi: 10.1023/a:1017960306927.
PMID:11865321
Abstract
We compared the content of high molecular microtubule-associated protein-2 and its phosphorylation by cAMP- and Ca(2+)/calmodulin-dependent protein kinases in the brain of DBA/2J and C57Bl/6 inbred mice. The revealed differences in protein content and phosphorylation can be attributed to the mechanisms mediating audiogenic seizures in DBA/2J mice and to differential sensitivity of these inbred lines to seizure-inducing factors.
摘要
Zotero 插件