Meyer-Hermann Michael
Institut für TheoretischePhysik, Dresden, Germany.
Immunol Cell Biol. 2002 Feb;80(1):30-5. doi: 10.1046/j.1440-1711.2002.01052.x.
A general criterion is formulated to decide if the recycling of B cells exists in germinal centre (GC) reactions. The criterion is independent of the selection and affinity maturation process and based solely on total centroblast population arguments. An experimental test is proposed to verify whether the criterion is fulfilled.
制定了一个通用标准来判定生发中心(GC)反应中是否存在B细胞的循环利用。该标准独立于选择和亲和力成熟过程,仅基于总中心母细胞群体的论据。提出了一项实验测试以验证该标准是否得到满足。