Phillips D I, Davies M J, Robinson J S
MRC Unit (University of Southampton), Southampton General Hospital, UK.
Twin Res. 2001 Oct;4(5):327-31. doi: 10.1375/1369052012669.
Although there is substantial evidence from studies of singletons that small size at birth is linked with long-term adverse health effects, until recently little was known as to whether these associations extend to twins. A review of published studies suggests that at present there is little consistent evidence that birthsize in twins is associated with increased morbidity or morality. While, these findings may reflect methodological limitations, it is also argued that they arise as a consequence of the substantially different biology of fetal growth in twins.
尽管来自单胎研究的大量证据表明出生时体型小与长期不良健康影响有关，但直到最近，对于这些关联是否也适用于双胞胎却知之甚少。一项对已发表研究的综述表明，目前几乎没有一致的证据表明双胞胎的出生体型与发病率或死亡率增加有关。虽然，这些发现可能反映了方法学上的局限性，但也有人认为它们是双胞胎胎儿生长生物学存在显著差异的结果。
