Lyons R A, Djahanbakhch O, Mahmood T, Saridogan E, Sattar S, Sheaff M T, Naftalin A A, Chenoy R
Academic Department of Obstetrics and Gynaecology, St Bartholomew's and The Royal London Hospital School of Medicine and Dentistry, Whitechapel, London E1 1BB, UK.
Hum Reprod. 2002 Mar;17(3):584-8. doi: 10.1093/humrep/17.3.584.
The cyclical changes in ciliary structure and motion within the human Fallopian tube are well documented. Previous investigators have studied ciliary beat frequency (CBF) in relation to menstrual cycle and anatomical site, but with conflicting results.
Using a technique that records variations in light intensity, we have studied the changes in CBF in relation to the menstrual cycle and anatomical site. Fallopian tubes were collected from 26 women who underwent hysterectomy for benign conditions. Menstrual history, hormone profile and endometrial biopsy results were used to determine the stage of the cycle. Fourteen women were in the proliferative phase, and 12 women in the secretory phase.
Mean CBF for all subjects was 5.3 plus minus 0.2 Hz. There was no significant difference in CBF in relation to anatomical site. In the fimbrial region the ciliary beat was faster in the secretory (5.8 plus minus 0.3 Hz) as compared with the proliferative phase (4.9 plus minus 0.2 Hz), P < 0.02.
It is possible that this increase in fimbrial CBF may contribute to ovum retrieval and transport after ovulation. However, the reproductive significance of the changes in CBF in relation to the menstrual cycle needs further investigation.
人体输卵管内纤毛结构和运动的周期性变化已有充分记录。先前的研究人员已研究了纤毛摆动频率（CBF）与月经周期及解剖部位的关系，但结果相互矛盾。
我们采用一种记录光强度变化的技术，研究了CBF与月经周期及解剖部位的关系。从26名因良性疾病接受子宫切除术的女性身上采集输卵管。月经史、激素水平和子宫内膜活检结果用于确定月经周期阶段。14名女性处于增殖期，12名女性处于分泌期。
所有受试者的平均CBF为5.3±0.2赫兹。CBF与解剖部位无关，无显著差异。在伞端区域，分泌期（5.8±0.3赫兹）的纤毛摆动比增殖期（4.9±0.2赫兹）更快，P<0.02。
伞端CBF的这种增加可能有助于排卵后卵子的拾取和运输。然而，CBF变化与月经周期的生殖意义需要进一步研究。
