病毒RNA迁移至分离的小鼠肝线粒体后烟草花叶病毒外壳蛋白的合成
Synthesis of tobacco mosaic virus coat protein following migration of viral RNA into isolated mouse liver mitochondria.
作者信息
Dimitriadis G J, Georgatsos J G
出版信息
Nucleic Acids Res. 1975 Oct;2(10):1719-26. doi: 10.1093/nar/2.10.1719.
Abstract
RNA of Tobacco Mosaic Virus is shown to be able to migrate into isolated mouse liver mitochondria, whence it can be reisolated intact. The migration of RNA is accompanied by enhanced rate of protein synthesis, which is sensitive to chloramphenicol, but not to cycloheximide. Evidence is presented showing that, among the products formed is the coat protein of Tobacco Mosaic Virus.
摘要
烟草花叶病毒的RNA能够迁移到分离出的小鼠肝脏线粒体中，并且能从中完整地重新分离出来。RNA的迁移伴随着蛋白质合成速率的提高，这种提高对氯霉素敏感，但对放线菌酮不敏感。有证据表明，所形成的产物中有烟草花叶病毒的外壳蛋白。
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