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伴有平滑肌增生的海绵状胰管扩张症导致复发性急性胰腺炎。

Cavernous pancreatic ductal ectasia with smooth muscle proliferation causing recurrent acute pancreatitis.

作者信息

Sugiyama M, Izumisato Y, Abe N, Terado Y, Fujioka Y, Ogawa T, Nakamura T, Atomi Y

机构信息

First Department of Surgery, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.

出版信息

Int J Pancreatol. 2001;29(2):99-105. doi: 10.1385/IJGC:29:2:099.

DOI:10.1385/IJGC:29:2:099
PMID:11876255
Abstract

BACKGROUND

Pancreatic cystic lesions have various etiologies, including pseudocyst (inflammatory cyst), retention cyst, congenital cyst, and neoplastic cyst.

RESULTS

This report describes a previously unreported, unique pancreatic cyst-like lesion causing recurrent acute pancreatitis. A 23-yr-old man had an 8 x 5 x 3-cm pancreatic head mass which contained multiple 3-7-mm cysts communicating with the main pancreatic duct on imaging studies. Pancreatoduodenectomy with mass excision prevented further attacks of acute pancreatitis. Pathological examination showed multiple cystic dilatations of branch pancreatic ducts surrounded by proliferating smooth muscle tissue, probably associated with hamartomatous changes.

CONCLUSION

We consider the present lesion to represent cavernous pancreatic ductal ectasia with smooth muscle proliferation because of its striking cholangiopancreatographic similarity to Caroli disease.

摘要

背景

胰腺囊性病变有多种病因,包括假性囊肿(炎性囊肿)、潴留性囊肿、先天性囊肿和肿瘤性囊肿。

结果

本报告描述了一种此前未报道的、独特的胰腺囊肿样病变,可引起复发性急性胰腺炎。一名23岁男性有一个8×5×3 cm的胰头肿物,影像学检查显示其中有多个3 - 7 mm的囊肿与主胰管相通。行胰十二指肠切除术并切除肿物后,未再发生急性胰腺炎发作。病理检查显示分支胰管多处囊性扩张,周围有增生的平滑肌组织,可能与错构瘤样改变有关。

结论

由于该病变在胰胆管造影上与卡罗里病有显著相似性,我们认为目前的病变代表伴有平滑肌增生的海绵状胰管扩张。

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Int J Pancreatol. 2001;29(2):99-105. doi: 10.1385/IJGC:29:2:099.
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引用本文的文献

1
Caroli Disease: A Presentation of Acute Pancreatitis and Cholangitis.卡罗里病:急性胰腺炎和胆管炎的一种表现形式。
Cureus. 2020 Jul 11;12(7):e9135. doi: 10.7759/cureus.9135.

本文引用的文献

1
Intraductal papillary mucinous tumors of the pancreas: imaging studies and treatment strategies.胰腺导管内乳头状黏液性肿瘤:影像学研究与治疗策略
Ann Surg. 1998 Nov;228(5):685-91. doi: 10.1097/00000658-199811000-00008.
2
Multicystic pancreatic hamartoma: a distinctive lesion with immunohistochemical and ultrastructural study.
Hum Pathol. 1992 Nov;23(11):1309-12. doi: 10.1016/0046-8177(92)90301-i.