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[黄斑疾病中局部视网膜电图的检测]

[The testing of local electroretinogram in macular diseases].

作者信息

Luo G, Wu L, Wu D

机构信息

Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060.

出版信息

Zhonghua Yan Ke Za Zhi. 1998 Jan;34(1):42-4.

Abstract

OBJECTIVES

To record the local electroretinogram (LERG) in macular diseases, and define the using value of LERG in macular diseases.

METHODS

The LERGs of five kinds of maculopathies were recorded with a spot light stimulator at 2.5, 5.0, 7.5 degrees of macular region.

RESULTS

(1) The amplitudes of LERG at the three regions in Stargardt's disease, wet form age-related macular degeneration (AMD), central serous chorioretinopathy, and idiopathic macular hole were significantly lowered in comparison with the controls (P < 0.01). In the meanwhile, these diseases also showed high abnormal rates. While in dry form AMD and epiretinal membrane, the amplitudes of LERG had no significant changes (P > 0.05). (2) The abnormal rates of LERG were related to the stimulated area. In the three tested areas, the highest abnormal rates occurred at 2.5 degrees.

CONCLUSIONS

There are mean differences in macular electrical activities in these maculopathies. LERG is an effective method of electrophysiology for testing macular function.

摘要

目的

记录黄斑疾病的局部视网膜电图(LERG),并明确LERG在黄斑疾病中的应用价值。

方法

使用点光源刺激器在黄斑区2.5、5.0、7.5度处记录五种黄斑病变的LERG。

结果

(1)与对照组相比,Stargardt病、湿性年龄相关性黄斑变性(AMD)、中心性浆液性脉络膜视网膜病变和特发性黄斑裂孔在这三个区域的LERG振幅显著降低(P<0.01)。同时,这些疾病的异常率也较高。而干性AMD和视网膜前膜中,LERG振幅无显著变化(P>0.05)。(2)LERG的异常率与刺激区域有关。在三个测试区域中,异常率最高出现在2.5度处。

结论

这些黄斑病变的黄斑电活动存在均值差异。LERG是检测黄斑功能的一种有效的电生理方法。

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