Huang S, Wu D, Jiang F, Ma J, Wu L, Liang J, Luo G
Zhongshan Ophthalmic Center Sun Yat-sen University of Medical Sciences, Guangzhou, China.
Doc Ophthalmol. 2000 Sep;101(2):115-24. doi: 10.1023/a:1026587103165.
To measure and compare the multifocal electroretinogram in control group and patients with age-related maculopathies, 17 eyes of control subjects, 9 eyes of wet-form ARMD, 8 eyes of dry-form ARMD and 14 eyes of idiopathic macular hole were tested with VERIS Sciences 4.0. The latencies and average response densities of 6 ring retinal regions in control eyes were compared with those in ARMD and macular hole. The amplitude depression and latency prolongation were found in age-related maculopathies. The changes of multifocal ERG were dramatic in wet-form ARMD and moderate in dry-form ARMD and IMH, which were correspondent with the pathological changes of the diseases. Our results suggest that the multifocal electroretinogram can be used to quantity the visual function in age-related maculopathies.
为测量和比较对照组及年龄相关性黄斑病变患者的多焦视网膜电图，使用VERIS Sciences 4.0对17只对照者眼睛、9只湿性年龄相关性黄斑变性（ARMD）眼睛、8只干性ARMD眼睛和14只特发性黄斑裂孔眼睛进行了检测。将对照眼6个环形视网膜区域的潜伏期和平均反应密度与ARMD和黄斑裂孔患者的进行比较。在年龄相关性黄斑病变中发现了振幅降低和潜伏期延长。多焦视网膜电图的变化在湿性ARMD中显著，在干性ARMD和特发性黄斑裂孔中为中度，这与疾病的病理变化相对应。我们的结果表明，多焦视网膜电图可用于量化年龄相关性黄斑病变中的视觉功能。
