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[准分子激光角膜切削术后近视回退]

[Myopic regression after photorefractive keratectomy].

作者信息

Pang G, Zhan S, Li Y, Jin Y, Sun Y, Li W

机构信息

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730.

出版信息

Zhonghua Yan Ke Za Zhi. 1998 Nov;34(6):451-3.

Abstract

OBJECTIVE

To investigate myopic regression after excimer laser photorefractive keratectomy (PRK) in patients with myopia.

METHODS

103 eyes with regression (>or= -1.00 D) found in the follow-up for more than 1 year were included in this study. The preoperative spherical equivalent was -4.00 - -14.50 D (-8.72 +/- 2.65 D). Patients were divided into two groups: (1) moderate myopia (-4.00 - -7.90 D) and (2) high myopia (>or= -8.00 D).

RESULTS

A significant positive correlation was found between regression and the extent of attempted correction, the rate of regression in high myopia group was 6.93% and that in moderate group, 1.17%. The rate of regression in older age group was higher than that in younger cases. (P < 0.01). Relatively severe haze under the corneal epithelium often accompanies the regression, and decrease of the dosage of topical corticosteroid application or its withdrawal because of the development of corticosteroid ocular hypertention could lead to the regression. The stability of the refraction is not related to the difference in sex. The regression is often accompanied by the increase in K value.

CONCLUSION

The regression is significantly related to the extent of attempted correction, patients' age, corneal haze and topical application of corticosteroid.

摘要

目的

研究近视患者准分子激光屈光性角膜切削术(PRK)后近视回退情况。

方法

本研究纳入103只在随访1年以上出现回退(≥ -1.00 D)的眼睛。术前等效球镜度数为-4.00 - -14.50 D(-8.72 ± 2.65 D)。患者分为两组:(1)中度近视(-4.00 - -7.90 D)和(2)高度近视(≥ -8.00 D)。

结果

回退与尝试矫正的程度之间存在显著正相关,高度近视组的回退率为6.93%,中度近视组为1.17%。老年组的回退率高于年轻患者(P < 0.01)。角膜上皮下相对严重的 haze 常伴随回退出现,因糖皮质激素性高眼压的发生而减少局部糖皮质激素的用量或停药可导致回退。屈光稳定性与性别差异无关。回退常伴随 K 值升高。

结论

回退与尝试矫正的程度、患者年龄、角膜 haze 及局部应用糖皮质激素显著相关。

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