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近视患者准分子激光原位角膜磨镶术并发症及疗效的长期评估:8年随访

Long-term evaluation of complications and results of photorefractive keratectomy in myopia: an 8-year follow-up.

作者信息

Shojaei Ahmad, Mohammad-Rabei Hossein, Eslani Medi, Elahi Behzad, Noorizadeh Farsad

机构信息

Department of Ophthalmology, Baghyatolah University of Medical Sciences, Tehran, Iran.

出版信息

Cornea. 2009 Apr;28(3):304-10. doi: 10.1097/ICO.0b013e3181896767.

Abstract

PURPOSE

To evaluate 8-year results of photorefractive keratectomy (PRK) for myopia in terms of safety, efficacy, stability, and late complications.

METHODS

From 371 myopic eyes of 203 patients who underwent PRK using NIDEK EC-5000 excimer laser with 5.5- to 6-mm ablation zones in Basir Eye Center, Tehran, Iran, during 1997-1998, data of 179 myopic eyes of 98 patients, who participated in annual examinations, were analyzed. Treated eyes were divided into 3 groups according to preoperative refraction: low myopia [<or=-6.00 diopters (D)], moderate myopia (-6.10 to -10.00 D), and high myopia (>-10.00 D). The main outcome measures were safety, efficacy, stability, and postoperative complications.

RESULTS

Eight years after PRK, 69.64%, 44.44%, and 45.65% of the low, moderate, and high myopic groups were within +/-0.5 D of emmetropia. Sixteen eyes (4.31% of original cases) underwent retreatment mainly because of regression. Although a small myopic shift occurred up to 8 years after surgery, changes in myopic regression stabilized in all myopic groups within 24 months. Four eyes (2.06%) lost 2 lines of best spectacle-corrected visual acuity (1 eye for corneal haze and other 3 for problems not related to refractive surgery). Corneal haze occurred in 11.34% especially in medium and high myopic groups, but it cleared within 2 years in 68.2% of cases.

CONCLUSIONS

Based on our study, PRK seems to be a safe, efficient, and stable surgical procedure, and if patients obtain a good result with the initial treatment, then their results are relatively stable over time.

摘要

目的

从安全性、有效性、稳定性和晚期并发症方面评估准分子激光角膜切削术(PRK)治疗近视8年的效果。

方法

1997年至1998年期间,在伊朗德黑兰的巴锡尔眼科中心,对203例接受使用NIDEK EC - 5000准分子激光、消融区为5.5至6毫米的PRK手术的患者的371只近视眼睛进行研究,分析了其中98例患者的179只参与年度检查的近视眼睛的数据。根据术前屈光度将治疗眼分为3组:低度近视[≤ - 6.00屈光度(D)]、中度近视(- 6.10至- 10.00 D)和高度近视(>- 10.00 D)。主要观察指标为安全性、有效性、稳定性和术后并发症。

结果

PRK术后8年,低度、中度和高度近视组分别有69.64%、44.44%和45.65%的患者屈光不正度数在正视眼的±0.5 D范围内。16只眼(占原始病例的4.31%)主要因回退而接受再次治疗。尽管术后长达8年出现了小幅度的近视漂移,但所有近视组的近视回退变化在24个月内趋于稳定。4只眼(2.06%)最佳矫正视力下降了2行(1只眼因角膜混浊,另外3只眼因与屈光手术无关的问题)。角膜混浊发生率为11.34%,尤其在中度和高度近视组,但68.2%的病例在2年内混浊消退。

结论

根据我们的研究,PRK似乎是一种安全、有效且稳定的手术方法,如果患者初始治疗效果良好,那么随着时间推移其效果相对稳定。

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