Shojaei Ahmad, Mohammad-Rabei Hossein, Eslani Medi, Elahi Behzad, Noorizadeh Farsad
Department of Ophthalmology, Baghyatolah University of Medical Sciences, Tehran, Iran.
Cornea. 2009 Apr;28(3):304-10. doi: 10.1097/ICO.0b013e3181896767.
To evaluate 8-year results of photorefractive keratectomy (PRK) for myopia in terms of safety, efficacy, stability, and late complications.
From 371 myopic eyes of 203 patients who underwent PRK using NIDEK EC-5000 excimer laser with 5.5- to 6-mm ablation zones in Basir Eye Center, Tehran, Iran, during 1997-1998, data of 179 myopic eyes of 98 patients, who participated in annual examinations, were analyzed. Treated eyes were divided into 3 groups according to preoperative refraction: low myopia [<or=-6.00 diopters (D)], moderate myopia (-6.10 to -10.00 D), and high myopia (>-10.00 D). The main outcome measures were safety, efficacy, stability, and postoperative complications.
Eight years after PRK, 69.64%, 44.44%, and 45.65% of the low, moderate, and high myopic groups were within +/-0.5 D of emmetropia. Sixteen eyes (4.31% of original cases) underwent retreatment mainly because of regression. Although a small myopic shift occurred up to 8 years after surgery, changes in myopic regression stabilized in all myopic groups within 24 months. Four eyes (2.06%) lost 2 lines of best spectacle-corrected visual acuity (1 eye for corneal haze and other 3 for problems not related to refractive surgery). Corneal haze occurred in 11.34% especially in medium and high myopic groups, but it cleared within 2 years in 68.2% of cases.
Based on our study, PRK seems to be a safe, efficient, and stable surgical procedure, and if patients obtain a good result with the initial treatment, then their results are relatively stable over time.
从安全性、有效性、稳定性和晚期并发症方面评估准分子激光角膜切削术(PRK)治疗近视8年的效果。
1997年至1998年期间,在伊朗德黑兰的巴锡尔眼科中心,对203例接受使用NIDEK EC - 5000准分子激光、消融区为5.5至6毫米的PRK手术的患者的371只近视眼睛进行研究,分析了其中98例患者的179只参与年度检查的近视眼睛的数据。根据术前屈光度将治疗眼分为3组:低度近视[≤ - 6.00屈光度(D)]、中度近视(- 6.10至- 10.00 D)和高度近视(>- 10.00 D)。主要观察指标为安全性、有效性、稳定性和术后并发症。
PRK术后8年,低度、中度和高度近视组分别有69.64%、44.44%和45.65%的患者屈光不正度数在正视眼的±0.5 D范围内。16只眼(占原始病例的4.31%)主要因回退而接受再次治疗。尽管术后长达8年出现了小幅度的近视漂移,但所有近视组的近视回退变化在24个月内趋于稳定。4只眼(2.06%)最佳矫正视力下降了2行(1只眼因角膜混浊,另外3只眼因与屈光手术无关的问题)。角膜混浊发生率为11.34%,尤其在中度和高度近视组,但68.2%的病例在2年内混浊消退。
根据我们的研究,PRK似乎是一种安全、有效且稳定的手术方法,如果患者初始治疗效果良好,那么随着时间推移其效果相对稳定。