Yeming Wu, Somme Stig, Chenren Shi, Huiming Jin, Ming Zhu, Liu Donald C
Department of Surgery, Section of Pediatric Surgery, The University of Chicago, Chicago, IL, USA.
J Pediatr Surg. 2002 Mar;37(3):398-402. doi: 10.1053/jpsu.2002.30844.
BACKGROUND/PURPOSE: Esophageal stricture requiring dilatation often is the sequelae in children with a history of congenital or acquired esophageal anomalies. Balloon catheter dilatation (BCD) for esophageal stricture is well established in adults, yet its role in children is less well described. The authors report their initial experience using BCD in children with esophageal stricture, assessing outcome.
Between January 1994, and December 1998, 20 children (age range, 17 days to 12 years) underwent BCD for esophageal strictures and were divided into 2 etiology groups (A and B). (A, n = 10) included congenital anomalies (esophageal atresia, 10), and (B, n = 10) included acquired anomalies (caustic ingestion, 7; tight fundoplication, 2; peptic stricture, 1). BCD was performed in all cases under conscious sedation with a balloon catheter (6 to 25 mm) with fluoroscopy. Outcome parameters included number of dilatations; complications, ie, perforation; and success or failure of procedure. Success was defined as increasing intervals of age-appropriate food tolerance between dilatations, and failure was defined as abandonment of dilatation in favor of surgical intervention. Follow-up for A and B ranged from 6 to 42 months.
Seventeen of 20 (85.0%) underwent successful BCD. In A, 10 of 10 (100%) had complete resolution of symptoms with follow-up ranging from 6 to 42 months versus 7 of 10 (70.0%) in B with follow-up of 6.5 to 36 months. In A, number of dilatations ranged from 1 to 4 over an average period of 2 months. In B, number of dilatations ranged from 3 to 40 over periods ranging from 2 to 30 months. All 3 failures occurred in children with caustic ingestion, with 1 child suffering perforation requiring urgent surgical intervention.
Balloon catheter dilatation can be applied safely and effectively to children in whom esophageal strictures develop after repair of esophageal atresia. However, its use in children with acquired esophageal anomalies, notably caustic injury, is associated with higher complication and failure rates, necessitating greater caution and lower expectations.
背景/目的:需要扩张的食管狭窄常常是有先天性或后天性食管异常病史儿童的后遗症。球囊导管扩张术(BCD)治疗成人食管狭窄已得到充分认可,但其在儿童中的作用描述较少。作者报告了他们使用BCD治疗儿童食管狭窄的初步经验,并评估了治疗结果。
1994年1月至1998年12月期间,20名儿童(年龄范围为17天至12岁)因食管狭窄接受了BCD治疗,并被分为2个病因组(A组和B组)。(A组,n = 10)包括先天性异常(食管闭锁,10例),(B组,n = 10)包括后天性异常(腐蚀性物质摄入,7例;紧密型胃底折叠术,2例;消化性狭窄,1例)。所有病例均在清醒镇静下使用球囊导管(6至25毫米)并在荧光透视引导下进行BCD。结果参数包括扩张次数;并发症,即穿孔;以及手术的成功或失败。成功定义为两次扩张之间适合年龄的食物耐受间隔增加,失败定义为放弃扩张而选择手术干预。A组和B组的随访时间为6至42个月。
20例中有17例(85.0%)BCD治疗成功。A组中,10例中有10例(100%)症状完全缓解,随访时间为6至42个月,而B组中10例中有7例(70.0%)症状缓解,随访时间为6.5至36个月。A组的扩张次数在平均2个月的时间内为1至4次。B组的扩张次数在2至30个月的时间内为3至40次。所有3例失败均发生在腐蚀性物质摄入的儿童中,其中1名儿童发生穿孔,需要紧急手术干预。
球囊导管扩张术可安全有效地应用于食管闭锁修复术后发生食管狭窄的儿童。然而,其在有后天性食管异常尤其是腐蚀性损伤的儿童中的应用,并发症和失败率较高,需要更加谨慎并降低预期。