莱姆病与免疫接种的当前状况
Lyme disease and current aspects of immunization.
作者信息
Kamradt Thomas
机构信息
Deutsches Rheumaforschungszentrum Berlin and Medizinische Universitätsklinik m,S, Rheumatologie, Berlin, Germany.
出版信息
Arthritis Res. 2002;4(1):20-9. doi: 10.1186/ar379. Epub 2001 Sep 28.
Abstract
Lyme disease is a tick-borne multisystem disease that affects primarily the skin, nervous system, heart and joints. At least three species of Borrelia burgdorferi sensu lato, namely Borrelia burgdorferi sensu stricto, Borrelia garinii, and Borrelia afzelii, can cause the disease. This review will focus mainly on the pathophysiology of Lyme arthritis, the long-term outcome of Lyme disease, and the recently licensed vaccine against Lyme disease.
摘要
莱姆病是一种由蜱传播的多系统疾病，主要影响皮肤、神经系统、心脏和关节。至少三种狭义伯氏疏螺旋体，即狭义伯氏疏螺旋体、伽氏疏螺旋体和阿氏疏螺旋体，可引起该病。本综述将主要关注莱姆关节炎的病理生理学、莱姆病的长期预后以及最近获批的莱姆病疫苗。
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