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The ovarian androgen-producing cells: a 2001 perspective.

作者信息

Magoffin Denis A

机构信息

Department of Obstetrics and Gynecology, CSMC Burns and Allen Research Institute, UCLA School of Medicine, Los Angeles, California 90048-0750, USA.

出版信息

Rev Endocr Metab Disord. 2002 Jan;3(1):47-53. doi: 10.1023/a:1012700802220.

DOI:10.1023/a:1012700802220
PMID:11883104
Abstract
摘要

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Preantral follicles stimulate luteinizing hormone independent differentiation of ovarian theca-interstitial cells by an intrafollicular paracrine mechanism.窦前卵泡通过卵泡内旁分泌机制刺激卵巢膜间质细胞的促黄体生成素非依赖性分化。
Endocrine. 1995 Feb;3(2):107-12. doi: 10.1007/BF02990061.
2
Luteinizing hormone receptor, steroidogenesis acute regulatory protein, and steroidogenic enzyme messenger ribonucleic acids are overexpressed in thecal and granulosa cells from polycystic ovaries.黄体生成素受体、类固醇生成急性调节蛋白和类固醇生成酶信使核糖核酸在多囊卵巢的卵泡膜细胞和颗粒细胞中过表达。
J Clin Endocrinol Metab. 2001 Mar;86(3):1318-23. doi: 10.1210/jcem.86.3.7318.
3
卵巢膜细胞的谱系特化需要通过卵母细胞和颗粒细胞进行多细胞相互作用。
Nat Commun. 2015 Apr 28;6:6934. doi: 10.1038/ncomms7934.
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Stimulatory effect of insulin on theca-interstitial cell proliferation and cell cycle regulatory proteins through MTORC1 dependent pathway.胰岛素通过 MTORC1 依赖途径对间质细胞增殖和细胞周期调控蛋白的刺激作用。
Mol Cell Endocrinol. 2013 Feb 5;366(1):81-9. doi: 10.1016/j.mce.2012.12.004. Epub 2012 Dec 19.
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Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells.促黄体生成素/人绒毛膜促性腺激素介导的mTORC1信号激活是卵泡膜间质细胞合成雄激素所必需的。
Mol Endocrinol. 2012 Oct;26(10):1732-42. doi: 10.1210/me.2012-1106. Epub 2012 Jul 24.
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A macrophage and theca cell-enriched stromal cell population influences growth and survival of immature murine follicles in vitro.富含巨噬细胞和卵泡膜细胞的基质细胞群体影响体外培养的未成熟小鼠卵泡的生长和存活。
Reproduction. 2011 Jun;141(6):809-20. doi: 10.1530/REP-10-0483. Epub 2011 Mar 9.
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Mol Endocrinol. 2010 Sep;24(9):1782-93. doi: 10.1210/me.2010-0044. Epub 2010 Jul 21.
8
The mammalian ovary from genesis to revelation.从起源到呈现的哺乳动物卵巢。
Endocr Rev. 2009 Oct;30(6):624-712. doi: 10.1210/er.2009-0012. Epub 2009 Sep 23.
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Regulation of sterol regulatory element-binding transcription factor 1a by human chorionic gonadotropin and insulin in cultured rat theca-interstitial cells.人绒毛膜促性腺激素和胰岛素对培养的大鼠卵泡膜间质细胞中固醇调节元件结合转录因子1a的调控
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