Pawłowicz P, Stachowiak G, Bielak A, Wilczyński J
Kliniki Medycyny Matczyno-Płodowej Instytutu Centrum Zdrowia Matki Polki w Łodzi.
Ginekol Pol. 2001 Dec;72(12):983-8.
To determinate the influence of anthocyanins from chokeberry on the generation of serous autoantibodies to oxidized low density lipoproteins (oLAB) and fructose levels in semen of males with oligospermia.
Study group consisted of 38 males with oligospermia of who were randomly divided into 2 subgroups: in 22 subjects anthocyanins were administered, while 16 men were on placebo; control group consisted of 25 healthy male volunteers. We examined the level of oxidative stress measured by serum concentration of oLAB, together with fructose levels in semen.
In the anthocyanin group oLAB titres decreased from 1103 +/- 34 mU/ml before treatment to 742 +/- 24 mU/ml (1st month) and 724 +/- 23 mU/ml (2nd month), p < 0.01. In the placebo group oLAB titres were as follows--1094 +/- 21 mU/ml before treatment, 1114 +/- 36 mU/ml (1st month) and 1117 +/- 33 mU/ml (2nd month), p > 0.05; oLAB tires in the control group: 601 +/- 40 mU/ml before treatment, 609 +/- 38 mU/ml (1st month) and 609 +/- 38 mU/ml (2nd month), p > 0.05. In the anthocyanin group fructose levels in semen increased from 850 +/- 42 mg/ml before treatment to 1121 +/- 26* mg/ml (1st month) and 1230 +/- 27* mg/ml (2nd month), p < 0.05. In the placebo group fructose levels were as follows--832 +/- 36 mg/ml before treatment, 845 +/- 33 mg/ml (1st month) and 841 +/- 35 mg/ml (2nd month), p > 0.05; fructose levels in the control group: 1376 +/- 40 mg/ml before treatment, 1376 +/- 40 mg/ml (1st month) and 1388 +/- 37 mg/ml (2nd month), p > 0.05.
确定黑果腺肋花楸中的花青素对少精子症男性血清中氧化型低密度脂蛋白自身抗体（oLAB）生成及精液中果糖水平的影响。
研究组由38例少精子症男性组成，他们被随机分为2个亚组：22例受试者给予花青素，16例男性给予安慰剂；对照组由25名健康男性志愿者组成。我们检测了通过血清oLAB浓度测量的氧化应激水平以及精液中的果糖水平。
在花青素组中，oLAB滴度从治疗前的1103±34 mU/ml降至第1个月时的742±24 mU/ml和第2个月时的724±23 mU/ml，p<0.01。在安慰剂组中，oLAB滴度如下——治疗前为1094±21 mU/ml，第1个月时为1114±36 mU/ml，第2个月时为1117±33 mU/ml，p>0.05；对照组中的oLAB滴度：治疗前为601±40 mU/ml，第1个月时为609±38 mU/ml，第2个月时为609±38 mU/ml，p>0.05。在花青素组中，精液中的果糖水平从治疗前的850±42 mg/ml增至第1个月时的1121±26* mg/ml和第2个月时的1230±27* mg/ml，p<0.05。在安慰剂组中，果糖水平如下——治疗前为832±36 mg/ml，第1个月时为845±33 mg/ml，第2个月时为841±35 mg/ml，p>0.05；对照组中的果糖水平：治疗前为1376±40 mg/ml，第1个月时为1376±40 mg/ml，第2个月时为1388±37 mg/ml，p>0.05。
