Cyganek A, Wiczyńska-Zajac A, Jabiry-Zieniewicz Z, Marianowski L
I Katedry i Kliniki Połoznictwa i Ginekologii Akademii Medycznej w Warszawie.
Ginekol Pol. 2001 Dec;72(12A):1287-90.
During the past few years a great development of clinical transplantology has taken place. Organ transplantation permits the best and quickest biological, clinical and social rehabilitation of patients. The subsidence of hormonal disturbances, which are responsible for irregular ovarian cycles and ovulation, has been observed among women with stable graft function. Such patients often become capable of conceiving and possessing offspring. With an increasing frequency of such occurrences, the pregnancy and delivery in the female transplant recipients is now becoming one of the major problem of contemporary perinatology. The aim of this study was to summarize our experience with the pregnancy, delivery and the state of newborn in female kidney transplant recipients.
25 female kidney-transplant recipients who became pregnant were observed during pregnancy. The age of the patient was between 23 and 38 years. 32 pregnancies were followed up. The duration and complications of pregnancy, mode of delivery and newborns condition were analyzed.
Miscarriages were observed in 47% of cases. Among patients who got birth, premature delivery was observed in 53%. Two stillbirths took place. 91% neonates were born in good condition. Preterm delivery occurred in 53%. Average birth weight was lower then observed at healthy pregnant women. No congenital defects were observed.
In kidney transplant recipients who became pregnant the increased incidence of spontaneous abortion and preterm delivery was observed. Newborns delivered by those patients had decreased birth weight. No congenital defects were noted among those babies.
在过去几年中，临床移植学取得了巨大发展。器官移植能使患者获得最佳且最快的生物、临床和社会康复。在移植功能稳定的女性患者中，已观察到导致卵巢周期和排卵不规律的激素紊乱现象有所缓解。这类患者常常能够受孕并生育后代。随着此类情况越来越频繁地发生，女性移植受者的妊娠和分娩如今正成为当代围产医学的主要问题之一。本研究的目的是总结我们在女性肾移植受者妊娠、分娩及新生儿状况方面的经验。
对25例妊娠的女性肾移植受者在孕期进行了观察。患者年龄在23至38岁之间。共随访了32次妊娠。分析了妊娠的持续时间和并发症、分娩方式及新生儿状况。
47%的病例出现流产。在分娩的患者中，53%出现早产。发生了2例死产。91%的新生儿出生状况良好。早产发生率为53%。平均出生体重低于健康孕妇。未观察到先天性缺陷。
妊娠的肾移植受者中，自然流产和早产的发生率增加。这些患者所分娩的新生儿出生体重降低。这些婴儿中未发现先天性缺陷。
