[子宫内膜异位症女性的血清和腹腔液CA-125浓度]
[Serum and peritoneal fluid CA-125 concentration in women with endometriosis].
作者信息
Kraśnicki D
机构信息
Wolontariusz II Katedry i Kliniki Ginekologii, II Katedry i Kliniki Ginekologii A M we Wrocławiu.
出版信息
Ginekol Pol. 2001 Dec;72(12A):1365-9.
OBJECTIVE
To evaluate the clinical utility of CA-125 measurements in peritoneal fluid (PF) as an indicator of endometriosis.
DESIGN
CA-125 levels in paired serum and peritoneal fluid were assessed by IMx CA-125 Assay (ABBOTT).
PATIENTS
107 women with and without endometriosis, undergoing laparoscopy during the luteal phase of the menstrual cycle were selected for the study.
RESULTS
CA-125 levels in peritoneal fluid were higher than those found in serum and were significantly elevated (P < 0.05) in comparison to the control group. In women with endometriosis stage I-II and stage III-IV. CA-125 levels in serum were increased only in stage III-IV.
CONCLUSIONS
The sensitivity of the peritoneal fluid CA-125 test for endometriosis is higher than the respective serum test. The measurement of CA-125 levels in PF could be useful in the detection of the early stage endometriosis, which seems to be missed by the CA-125 serum test.
目的
评估腹膜液（PF）中CA - 125检测作为子宫内膜异位症指标的临床实用性。
设计
采用IMx CA - 125检测法（雅培公司）评估配对血清和腹膜液中的CA - 125水平。
患者
选取107例在月经周期黄体期接受腹腔镜检查的有或无子宫内膜异位症的女性进行研究。
结果
腹膜液中的CA - 125水平高于血清中的水平，与对照组相比显著升高（P < 0.05）。在I - II期和III - IV期子宫内膜异位症女性中，血清CA - 125水平仅在III - IV期升高。
结论
腹膜液CA - 125检测对子宫内膜异位症的敏感性高于相应的血清检测。检测腹膜液中CA - 125水平可能有助于早期子宫内膜异位症的检测，而CA - 125血清检测似乎会遗漏这一阶段的病例。
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