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良性黏膜类天疱疮——病例报告

Benign mucous membrane pemphigoid--a case report.

作者信息

Puranwasi R, Naidoo S

机构信息

Department of Community Dentistry, University of Stellenbosch, Tygerberg, South Africa.

出版信息

SADJ. 2001 Nov;56(11):554-6.

Abstract

Benign mucous membrane pemphigoid (BMMP) is a relatively rare, chronic vesiculobullous disease. It frequently affects postmenopausal women, although cases have been reported in younger individuals. Benign mucous membrane pemphigoid has a predilection to affect multiple mucosal surfaces including the gingivae, hard and soft palate, alveolar ridge, nose, pharynx, gastrointestinal tract, genitalia and the conjunctiva. It is seen clinically as bullae or erosions on the mucosae or gingivae. The bullae rupture after 24-48 hours and the erosions heal within 7-14 days, sometimes with scar formation. Scarring frequently occurs with ocular mucosa involvement and may contribute to blindness. In order to make a diagnosis, the clinical features must be correlated with microscopic and immunopathological findings. Benign mucous membrane pemphigoid is treated with high doses of corticosteroids and immunosuppressive agents. This paper is a presentation of a case report in a 36-year-old woman.

摘要

良性黏膜类天疱疮(BMMP)是一种相对罕见的慢性水疱大疱性疾病。它常累及绝经后女性,不过也有在较年轻个体中发病的报道。良性黏膜类天疱疮易累及多个黏膜表面,包括牙龈、硬腭和软腭、牙槽嵴、鼻、咽、胃肠道、生殖器及结膜。临床上表现为黏膜或牙龈上的水疱或糜烂。水疱在24 - 48小时后破裂,糜烂在7 - 14天内愈合,有时会形成瘢痕。眼部黏膜受累时常常会形成瘢痕,可能导致失明。为了做出诊断,临床特征必须与显微镜及免疫病理检查结果相结合。良性黏膜类天疱疮采用大剂量皮质类固醇和免疫抑制剂进行治疗。本文报告了一名36岁女性的病例。

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