Epting C L, Wolfe R R, Abman S H, Deutsch G H, Ivy D
Section of Pediatric Cardiology, The Pediatric Heart Lung Center, B100 The Children's Hospital, 1056 E, 19th Avenue, Denver, CO 80218, USA.
Pediatr Cardiol. 2002 Mar-Apr;23(2):182-5. doi: 10.1007/s00246-001-0044-9. Epub 2002 Feb 19.
We describe a 2-year-old child with severe pulmonary hypertension due to a patent ductus arteriosus (PDA) with plexiform lesions on lung biopsy. Despite high basal pulmonary vascular resistance with minimal responsiveness to inhaled nitric oxide and other vasodilators, and advanced plexogenic arteriopathy on lung biopsy, her pulmonary hypertension completely resolved after PDA ligation and during 8 years of follow-up.