Seibert Rachel L, Maisenbacher Herbert W, Prosek Robert, Adin Darcy B, Arsenault Wendy G, Estrada Amara H
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100126, Gainesville, FL 32610-0126, USA.
J Vet Cardiol. 2010 Apr;12(1):67-73. doi: 10.1016/j.jvc.2009.12.002. Epub 2010 Feb 25.
Closure of reversed patent ductus arteriosus (PDA) is generally accepted to be contraindicated due to case based evidence of worsened outcomes, but little is known about closure of left-to-right PDA with concurrent pulmonary hypertension (PH). This report describes three dogs presenting with varying severity of PH and clinical signs, all with documented left-to-right PDA. The PDA was closed in each case; either by surgical ligation or transarterial device occlusion, and follow up was available for a minimum of 8 months. Every case had a successful outcome with improvement or resolution of PH and associated clinical signs.
由于基于病例的证据表明逆向动脉导管未闭（PDA）闭合后预后恶化，一般认为逆向PDA闭合是禁忌的，但对于伴有并发肺动脉高压（PH）的左向右分流PDA的闭合情况却知之甚少。本报告描述了三只患有不同严重程度的PH和临床症状的犬，所有犬均记录有左向右分流的PDA。每只犬的PDA均成功闭合；要么通过手术结扎，要么通过经动脉装置封堵，并且至少随访了8个月。每例均获得成功结果，PH及相关临床症状得到改善或消除。
