Lamba Manisha, Beauchesne Luc M, Veinot John P
Division of Anatomical Pathology, Department of Laboratory Medicine, Ottawa Hospital, Ottawa, Ontario, Canada.
Cardiovasc Pathol. 2006 Nov-Dec;15(6):352-3. doi: 10.1016/j.carpath.2006.06.001.
An 82-year-old female patient with a history of deep vein thrombosis presented with progressive dyspnea. Echocardiogram demonstrated significant pulmonary hypertension and patent ductus arteriosus (PDA). There was considerable debate regarding the role of PDA in the patient's pulmonary hypertension. The patient died of heart failure a few months later. Autopsy demonstrated extensive chronic pulmonary thromboembolic disease. Pulmonary thromboemboli continue to be a diagnostic challenge despite modern diagnostic modalities. Autopsy continues to play a role in investigating unexplained clinical findings and in determining cause of death.
一位有深静脉血栓形成病史的82岁女性患者出现进行性呼吸困难。超声心动图显示有严重的肺动脉高压和动脉导管未闭（PDA）。关于PDA在该患者肺动脉高压中的作用存在相当大的争议。该患者在几个月后死于心力衰竭。尸检显示有广泛的慢性肺血栓栓塞性疾病。尽管有现代诊断方法，但肺血栓栓塞仍然是一个诊断挑战。尸检在调查无法解释的临床发现和确定死亡原因方面继续发挥作用。
