Raffelsieper B, Merten C, Mennel H-D, Hedde H-P, Menzel J, Bewermeyer H
Neurologische Klinik, Krankenhaus Merheim, Kliniken der Stadt Köln, Germany.
Anasthesiol Intensivmed Notfallmed Schmerzther. 2002 Mar;37(3):157-62. doi: 10.1055/s-2002-21800.
We describe the clinical course and outcome following decompressive craniectomy in six patients. Five patients suffered from severe intracranial hypertension due to middle cerebral artery infarction. In one patient the cause was bacterial meningoencephalitis. Acute clinical and neuroradiological signs of intracranial hypertension were seen in all cases. Following ineffective conventional brain edema therapy, decompressive craniectomy was undertaken. In five cases intracranial pressure was sufficiently lowered. One patient developed transtentorial herniation with subsequent brain death. Four patients with middle artery infarction showed moderate neurological disorders and one patient with bacterial meningoencephalitis recovered completely after treatment. Craniectomy in malignant middle artery infarction should be taken into consideration if conventional brain edema therapy does not sufficiently reduce critically raised intracranial pressure. Craniectomy provides development of brain herniation. This treatment may reduce high lethality rate and high frequency of severe neurological disorders.
我们描述了6例患者行去骨瓣减压术后的临床过程及结果。5例患者因大脑中动脉梗死导致严重颅内高压。1例患者的病因是细菌性脑膜脑炎。所有病例均出现颅内高压的急性临床和神经放射学征象。在常规脑水肿治疗无效后,进行了去骨瓣减压术。5例患者颅内压得到充分降低。1例患者发生小脑幕切迹疝并随后脑死亡。4例大脑中动脉梗死患者出现中度神经功能障碍,1例细菌性脑膜脑炎患者治疗后完全康复。如果常规脑水肿治疗不能充分降低急剧升高的颅内压,应考虑对恶性大脑中动脉梗死患者行去骨瓣减压术。去骨瓣减压术可导致脑疝形成。这种治疗可能降低高致死率和严重神经功能障碍的高发生率。