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一名15岁患脑膜炎奈瑟菌性脑膜炎男孩的去骨瓣减压术及早期颅骨成形术

Decompressive craniectomy and early cranioplasty in a 15-year-old boy with N. meningitidis meningitis.

作者信息

Hoehne Julius, Friedrich Monika, Brawanski Alexander, Melter Michael, Schebesch Karl-Michael

机构信息

Department of Neurosurgery, University Medical Center Regensburg, Franz-Josef-Strauss Allee 11, 93053 Regensburg, Germany.

Department of Pediatrics, University Medical Center Regensburg, Franz-Josef-Strauss Allee 11, 93053 Regensburg, Germany.

出版信息

Surg Neurol Int. 2015 Apr 9;6:58. doi: 10.4103/2152-7806.154776. eCollection 2015.

Abstract

BACKGROUND

Intracranial hypertension is a well-known life-threatening complication of bacterial meningitis. Investigations on decompressive craniectomy after failure of conservative management are scarce, but this surgical treatment should be considered and performed expeditiously, as it lowers the intracranial pressure and improves brain tissue oxygenation. Early cranioplasty can further aid the rehabilitation.

CASE DESCRIPTION

A 15-year-old boy was admitted to our emergency department because of sudden onset of neurologic decline and consecutive loss of consciousness. Clinical examination and imaging showed elevated intracranial pressure, leading to the suspected diagnosis of meningitis. Intracranial pressure monitoring was installed, but the initiated conservative management failed. Finally, the patient underwent bilateral decompressive craniectomy. The microbiological test showed growth of Neisseria meningitidis. After full neurologic recovery, cranioplasty with two CAD/CAM titanium implants was conducted successfully.

CONCLUSIONS

This unique report shows that decompressive craniotomy with duroplasty may be a crucial therapeutic approach in bacterial meningitis with refractory increased intracranial pressure and brainstem compression. Early cranioplasty with a patient-specific implant allowed the early and full reintegration of the patient.

摘要

背景

颅内高压是细菌性脑膜炎一种众所周知的危及生命的并发症。关于保守治疗失败后减压性颅骨切除术的研究较少,但这种手术治疗应被考虑并尽快实施,因为它可降低颅内压并改善脑组织氧合。早期颅骨修补术可进一步促进康复。

病例描述

一名15岁男孩因突发神经功能衰退并继而昏迷被收入我院急诊科。临床检查和影像学检查显示颅内压升高,疑似脑膜炎诊断。安装了颅内压监测装置,但开始的保守治疗失败。最后,患者接受了双侧减压性颅骨切除术。微生物检测显示脑膜炎奈瑟菌生长。在神经功能完全恢复后,成功进行了使用两个计算机辅助设计/制造钛植入物的颅骨修补术。

结论

这份独特的报告表明,带硬脑膜成形术的减压性开颅术可能是治疗细菌性脑膜炎伴难治性颅内压升高和脑干受压的关键治疗方法。使用患者特异性植入物的早期颅骨修补术使患者能够早期并完全重新融入社会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f89f/4399170/62cdc9cf0300/SNI-6-58-g001.jpg

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