Amaya Misato, Okubo Yukari, Koga Michiyuki
Department of Dermatology, Tokyo Medical University, Japan.
J Dermatol. 2002 Feb;29(2):79-85. doi: 10.1111/j.1346-8138.2002.tb00170.x.
A 78-year-old woman, who had first noticed asymptomatic eruptions on her neck and shoulders eight years earlier, presented with papules and nodules 2 to 20 mm in diameter that had a normal to white hue and were flatly elevated. These lesions were scattered and multiple, some forming confluent plaques. Histopathologically, the epidermis was slightly atrophied, and collagen fibers in the dermis were coarse and proliferated. In addition, the number of elastic fibers was slightly decreased. No complications were evident. Based on these findings, the patient was given a diagnosis of mild eruptive collagenoma, a type of connective tissue nevus according to the classification of Uitto. This case is unique in that onset was at an advanced age and that distribution was localized on the neck and shoulders.
一名78岁女性，8年前首次注意到颈部和肩部出现无症状皮疹，现出现直径2至20毫米的丘疹和结节，颜色正常至白色，扁平隆起。这些损害散在多发，部分融合成斑块。组织病理学检查显示，表皮轻度萎缩，真皮内胶原纤维粗大且增生。此外，弹性纤维数量略有减少。未发现明显并发症。基于这些发现，该患者被诊断为轻度发疹性胶原瘤，根据乌伊托分类属于结缔组织痣的一种。该病例的独特之处在于发病年龄较大且分布局限于颈部和肩部。
