Wichniak Adam, Geisler Peter, Tracik Ferenc, Crönlein Tatjana, Morrissey Sean P, Zulley Jürgen
Sleep Disorders Centre, Department of Psychiatry, University of Regensburg, Universitätsstr. 84, 93053, Regensburg, Germany.
Physiol Behav. 2002;75(1-2):183-8. doi: 10.1016/s0031-9384(01)00635-7.
According to its guidelines, the Multiple Sleep Latency Test (MSLT) should be performed following an all-night polysomnography (PSG). However, the sleep quality and consequently the MSLT results may be affected by PSG and by the fact that a subject sleeps under unfamiliar conditions. The aim of this study was to examine whether PSG performed in a sleep laboratory has any influence on the MSLT and other measures of daytime sleepiness.
Twenty healthy subjects with a mean age of 35.9+/-10.1 years underwent two MSLT examinations, and the 2 examination days were at least 4 weeks apart. In addition, on each occasion a monotonous vigilance task (VT) was performed and the subjects were asked to fill out the Epworth Sleepiness (ESS) and Visual Analogue Scales (VAS). In a cross-over design, a group of 10 subjects underwent a MSLT (MSLT-P) following a PSG and, on a second occasion, a MSLT (MSLT-N) was performed without a prior PSG. Vice versa, a second group of 10 subjects underwent first MSLT-N and then MSLT-P.
None of the MSLT parameters differed significantly between MSLT-P and MSLT-N. The other measures of daytime sleepiness (VT, ESS, VAS) also showed no evidence of significant differences between days with and without a prior PSG.
The results of MSLT and other measures of daytime sleepiness in healthy subjects are not influenced by the fact whether or not the subjects had a PSG the night prior to MSLT.
根据其指南，多次睡眠潜伏期试验（MSLT）应在整夜多导睡眠图（PSG）之后进行。然而，睡眠质量以及MSLT结果可能会受到PSG以及受试者在不熟悉环境中睡眠这一事实的影响。本研究的目的是检验在睡眠实验室进行的PSG是否对MSLT及其他白天嗜睡测量指标有任何影响。
20名平均年龄为35.9±10.1岁的健康受试者接受了两次MSLT检查，两次检查日相隔至少4周。此外，每次检查时均进行了单调警觉任务（VT），并要求受试者填写爱泼华嗜睡量表（ESS）和视觉模拟量表（VAS）。采用交叉设计，一组10名受试者在PSG后进行MSLT（MSLT-P），第二次在未进行PSG的情况下进行MSLT（MSLT-N）。反之，另一组10名受试者先进行MSLT-N，然后进行MSLT-P。
MSLT-P和MSLT-N之间的MSLT参数均无显著差异。其他白天嗜睡测量指标（VT、ESS、VAS）在有或无PSG的日子之间也没有显著差异的证据。
健康受试者的MSLT结果及其他白天嗜睡测量指标不受受试者在MSLT前一晚是否进行PSG这一事实的影响。
