De Gennaro Luigi, Devoto Alessandra, Lucidi Fabio, Violani Cristiano
Dipartimento di Psicologia, Sezione di Neuroscienze, Università degli Studi di Roma 'La Sapienza', Roma, Italy.
J Sleep Res. 2005 Jun;14(2):107-12. doi: 10.1111/j.1365-2869.2005.00444.x.
Sleep onsets in the diurnal multiple sleep latency test (MSLT), following different sleep lengths of the preceding night sleep (8, 5, 4, 3, 2, 1 h) and following the corresponding recovery nights, were considered for a study on changes of oculomotor activity during sleep onset. The study aimed to assess the individual time course in spontaneous blinks (SBs) and slow eye movements (SEMs) during the sleep onset period and also the relationship with sleep latencies in the MSLT. Group analyses compared oculomotor changes between conditions characterized by a different level of daytime sleepiness. The results show a clear inverse relation between the two oculomotor measures, with a linear SB decrease and quadratic SEM increase across the wake-sleep transition. A 150 s sample of SB and SEM activity at the start of MSLT trials correlates with individual subsequent sleep latency. Finally, mean changes in daytime sleepiness as measured by the MSLT are paralleled by coherent oculomotor changes, with a significant linear decrease of SB as sleepiness increases as a consequence of previous sleep reduction. Both individual and group results show that endogenous blinking is associated with moderate changes in daytime sleepiness.
在昼夜多次睡眠潜伏期试验（MSLT）中，考虑到前一晚不同的睡眠时长（8、5、4、3、2、1小时）以及相应的恢复夜后，对入睡时的眼球运动活动变化进行了一项研究。该研究旨在评估入睡期间自发眨眼（SBs）和慢眼动（SEMs）的个体时间进程，以及与MSLT中睡眠潜伏期的关系。分组分析比较了以不同程度的日间嗜睡为特征的条件之间的眼球运动变化。结果显示，在从清醒到睡眠的转变过程中，这两种眼球运动指标之间存在明显的负相关关系，即SB呈线性下降，而SEM呈二次方增加。MSLT试验开始时150秒的SB和SEM活动样本与个体随后的睡眠潜伏期相关。最后，MSLT所测量的日间嗜睡的平均变化与连贯的眼球运动变化平行，随着因先前睡眠减少而导致的嗜睡增加，SB显著线性下降。个体和分组结果均表明，内源性眨眼与日间嗜睡的适度变化相关。
